Missouri · BLS May 2025

Registered Nurse Salary in Missouri

Also called RN, nurse. SOC 29-1141.

The Bureau of Labor Statistics counted 76,310 registered nurses working in Missouri. Here is what they are paid, what the median leaves after federal, state and FICA tax, and what that is worth against local prices.

Median pay · Missouri

$81,780A year, or $39.32 an hour.
Take-home a month$5,292After federal, state and FICA tax at 22.4%
Worth at national prices$90,049Prices here sit at 90.8 against 100
Against the nation16.2% belowNational median $97,550
What registered nurses earn in Missouri, May 2025
PercentileAnnualHourly
10th percentileEntry and lowest-paid$63,230$30.40
25th percentile$76,050$36.56
MedianHalf earn more, half less$81,780$39.32
75th percentile$98,560$47.39
90th percentileMost experienced and senior$104,390$50.19
MeanThe average, pulled up by the top$85,900$41.30
How we got this
  1. Median wage in MissouriBLS OEWS May 2025. Half of registered nurses earned more than this, half less.$81,780
  2. Median hourly wagePublished separately by BLS, not divided out of the annual figure.$39.32
  3. Take-home after federal, state and FICA tax$5,292 a month at an effective rate of 22.4%.$63,499 a year
  4. Worth at national average pricesPrices in Missouri sit at 90.8 against a national 100 (BEA, 2024).$90,049
  5. Against the national medianThe national median is $97,550.16.2% below
  6. Jobs countedA concentration of 1.2 against the nation's 1.00.76,310
What we assumed
  • Wages are BLS OEWS survey estimates for May 2025, not job postings or offers.
  • OEWS surveys wage and salary workers. The self-employed and business owners are outside it.
  • Take-home assumes one 2026 filer, filing single, taking the standard deduction, with no dependents, pre-tax retirement contributions or local income tax.
  • Regional price parities compare price levels between places in one year. They are not inflation, and they do not adjust for what a household actually buys.
Technical details

Method occupation-wage-v1Data bls-oews-2025-05-v1, us-tax-2026-v1, bea-rpp-2024-v1, census-acs5-2024-v1

What lands in the bank

A $81,780 salary in Missouri, for one single filer taking the standard deduction in 2026.

  • Federal income tax. $9,162 a year.
  • State income tax. $2,863 a year.
  • Social Security and Medicare. $6,256 a year.
  • Left over. $63,499 a year, $5,292 a month, an effective rate of 22.4%.

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What $81,780 is worth in Missouri

Prices in Missouri sit at 90.8 against a national average of 100, so $81,780 earned here buys what $90,049 buys at national average prices.

  • Rents. 69.9 against 100, the component that moves most between states.
  • Against local households. The median household in Missouri takes in $70,702, so this occupation's median is 1.16 times that, on one income.
  • How common the job is here. 20% more concentrated in Missouri than in the country as a whole.

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Common questions

Registered Nurse pay in Missouri, answered

How much does a registered nurse make in Missouri?

The median wage for registered nurses in Missouri is $81,780 a year, or $39.32 an hour.

Half earn more than that and half earn less. The figure comes from the Bureau of Labor Statistics occupational wage survey for May 2025.

What is the take-home pay for a registered nurse in Missouri?

On the median wage of $81,780, one filer taking the standard deduction keeps about $63,499 a year, or roughly $5,292 a month.

That is after federal, state and FICA tax, an effective rate of 22.4%.

Missouri takes $2,863 of it in state income tax.

Do registered nurses earn more in Missouri than in the rest of the country?

No. The median in Missouri is 16.2% below the national median of $97,550.

Nominal pay is only half the comparison: prices in Missouri sit at 90.8 against a national 100, so the gap in what the money buys is different from the gap in the salary.

Is $81,780 a good salary in Missouri?

It is 1.16 times the median household income of $70,702. A household often has more than one earner, so a single salary at this level goes further than the ratio alone suggests.

Prices in Missouri run at 90.8 against a national average of 100, with rents at 69.9, so $81,780 here buys about what $90,049 buys at national average prices.

What do the highest-paid registered nurses earn in Missouri?

The top tenth earn $104,390 a year or more, against $63,230 at the bottom tenth.

Experience, specialism, employer and the part of Missouri someone works in all move a wage inside that range; the survey reports the spread, not the reason for it.

How many registered nurses are there in Missouri?

The survey counted 76,310 of these jobs in Missouri for May 2025.

That makes the occupation 20% more concentrated here than in the country as a whole. It counts wage and salary jobs, so the self-employed are outside it.

Sources

Where this data comes from